People who love travelling to tropical countries are no stranger to the mangosteen fruit. This unique tropical flavour has been transported directly from Thailand to Taiwan since last year, allowing people to enjoy it without having to leave the country. What's more, Hsieh Jung-hung, associate dean of the School of Nutrition at Taipei Medical University, pointed out that the rind of the mangosteen, which has always been regarded as inedible, can in fact be extracted to produce a combination of excellent antioxidant effect andGlucose stabilisationThe "santonin" effect adds more health value to this fruit.
In fact, fruits have the ability to protect themselves. In order to defend themselves against pests, bacteria and ultraviolet rays from the sun, the shell and seeds of fruits have evolved over time into a solid "fortress of protection", which often contains special antioxidant components.
However, not all of these valuable antioxidants can be absorbed by the body through direct consumption of the fruit. Mangosteen, for example, has a solid outer skin that effectively protects it from many types of external damage, and research conducted by the Laboratory of the School of Nutrition at the Taipei Medical University has further confirmed that mangosteen is rich in sanguinarine in its shell and core, which is the highest among all fruits and vegetables, so it can be said to be a "hidden treasure".
"Oxidation is arguably the greatest threat to human ageing! Tse Wing Hung emphasised that in order to understand the benefits of santonin, it is important to recognise the effects of oxidation on the human body. In our daily life, smoking, air pollution, water pollution, radiation (such as X-rays, ultraviolet rays), pesticide exposure, long-term stressful life, excessive exercise intensity and other factors will lead to an increase in the concentration of free radicals in the human body, a state known as "oxidative stress".
The higher the oxidative stress, the higher the number of free radicals in the body. Numerous domestic and international studies have confirmed that excessive free radicals pose a serious threat to human health by increasing the risk of various diseases, such as cancers, cardiovascular diseases (e.g., coronary arteriosclerosis, vascular embolism), and neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease), and so on.
TSE Wing-hung further explained that mangosteen is not only round and lovely in shape and colour, but also juicy and sweet in flesh, while the often-neglected kernel and the outer skin of the fruit can be purified to obtain the powerful anti-oxidant sanguinarine, which has shown great potential in the prevention of many diseases.
在Blood Sugar ControlIn this regard, the performance of ketones is even more impressive. The research team from Taipei Medical University conducted experiments with mangosteen extract containing high concentrations of sanguinarine, and found that after 8 weeks of observation, compared with the control group of rats that did not ingest the extract, the blood glucose of the three groups of rats that ingested low, medium, and high doses of the extract showed significant decreases: the low dose group decreased by 14%, the medium dose group decreased by 25.6%, and the high dose group decreased by 27.6%; at the same time, the insulin resistance of these three groups also decreased by 18.6%, 30.1%, and 30.1%, respectively. This result shows that the intake of sanguinone can help to improve the insulin sensitivity of the body, which in turn can help the body to regulate the blood glucose level normally.
"With its strong antioxidant capacity, sanguinarine can reduce the number of free radicals in the body, thereby protecting the pancreatic β-cells," said Mr Tse. Tse Wing Hung explained the rationale behind, pancreatic beta cells are the key cells responsible for the secretion of insulin, once these cells are damaged and lead to abnormal function, it will affect the body's glucose metabolism, which may not only trigger diabetes, but also aggravate the condition of those who already have the disease.
Dietitian Li Wan Ting shared her own case, her father's original fasting blood glucose value was as high as 120 or more, after a period of time of regular use of ketones extract, the blood glucose value has dropped significantly, which fully proves the actual effect of ketones in regulating blood glucose.
Currently, relevant cellular and animal experiments conducted by the Taipei Medical University have confirmed that mangosteen has the function of regulating and controlling physiological indicators such as blood glucose, blood pressure, blood lipids, etc., as well as improving the body's allergic reactions. Although the rind of the mangosteen is not directly edible, with the development of extraction technology, it is expected that more products with both therapeutic and nutritional effects will be developed from it in the future, so that the health value of the mangosteen can be more fully utilised.
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