Need folic acid (ie vitamin B9) and B12. The growth of red blood cells requires folic acid, which is a coenzyme necessary for regulating cell metabolism and cell division.
When folic acid and B12 are lacking, the synthesis of nucleated red blood cell DNA in the bone marrow will be hindered, leading to red blood cell differentiation, slowing down of reproduction speed, and megaloblastic anemia.
*Folic acid needs to be supplemented with folic acid (ie vitamin B9). The growth of red blood cells requires folic acid, which is a coenzyme necessary for regulating cell metabolism and cell division.
*The role of vitamin B12 is to increase the utilization of folic acid in the body. When folic acid and B12 are deficient, the DNA synthesis of nucleated erythrocytes in the bone marrow will be hindered, resulting in the slowing of red blood cell differentiation and reproduction, and megaloblastic anemia.